Pharmaco‐genetic inhibition of pyramidal neurons retards hippocampal kindling‐induced epileptogenesis
نویسندگان
چکیده
منابع مشابه
Effect of repeated transcranial magnetic stimulation during epileptogenesis on spontaneous activity of hippocampal CA1 pyramidal neurons in rats
Introduction: Considering the antiepileptogenic effects of repeated transcranial magnetic stimulation (rTMS), the effect of rTMS applied during amygdala kindling on spontaneous activity of hippocampal CA1 pyramidal neurons was investigated. Materials and Methods: A tripolar electrode was inserted in basolateral amygdala of Male Wistar rats. After a recovery period, animals received daily kindl...
متن کاملeffect of repeated transcranial magnetic stimulation during epileptogenesis on spontaneous activity of hippocampal ca1 pyramidal neurons in rats
introduction: considering the antiepileptogenic effects of repeated transcranial magnetic stimulation (rtms), the effect of rtms applied during amygdala kindling on spontaneous activity of hippocampal ca1 pyramidal neurons was investigated. materials and methods: a tripolar electrode was inserted in basolateral amygdala of male wistar rats. after a recovery period, animals received daily kindli...
متن کاملEffects of resveratrol on intrinsic neuronal properties of CA1 pyramidal neurons in rat hippocampal slices
Introduction: Resveratrol (3,5,4-trihydroxystilbene) a non-flavonoid polyphenol found in some plants like grapes, peanuts and pomegranates, possesses a wide range of biological effects. Evidence indicates that resveratrol has beneficial effects on nervous system to induce neuroprotection. However, the cellular mechanisms of the effects are not fully determined. In the present study, the cellula...
متن کاملAntibiotic Supplements Affect Electrophysiological Properties and Excitability of Rat Hippocampal Pyramidal Neurons in Primary Culture
Introduction: Antibiotic supplements are regularly used in neuronal culture media to control contamination however, they can interfere with the neuronal excitability and affect electrophysiological properties. Therefore, in this study, the effect of penicillin/streptomycin supplements on the spontaneous electrophysiological activity of hippocampal pyramidal neurons was examined. Methods: Electr...
متن کاملSize of hippocampal pyramidal neurons in schizophrenia.
BACKGROUND Meta-analyses of hippocampal size have indicated that this structure is smaller in schizophrenia. This could reflect a reduction in the size of constituent neurons or a reduced number of neurons. AIMS To measure the size of hippocampal pyramidal neurons in the brains of people with and without schizophrenia. METHOD Pyramidal neuron size in hippocampal subfields was estimated ster...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: CNS Neuroscience & Therapeutics
سال: 2020
ISSN: 1755-5930,1755-5949
DOI: 10.1111/cns.13434